top of page

The active ingredients of Kratom: What is Mitragynine?

The active ingredients of Kratom, a plant native to the rainforests of Southeast Asia, have gained popularity around the world in recent years, in part due to the compounds found in its leaves, particularly mitragynine. This compound is known for its diverse effects on the human body, both positive and potentially risky. In this post, we take a closer look at the effects of mitragynine and the importance of this compound in the context of kratom use.

The active ingredients of Kratom-What is Mitragynine?

Mitragynine is the main alkaloid found in the leaves of the kratom tree (Mitragyna speciosa). It interacts primarily with the opioid receptors in the brain, triggering a number of effects that are responsible for kratom's effects. Although mitragynine does not have the same chemical structure as opioids, it has similar effects, which explains why kratom is often used to relieve pain and manage withdrawal symptoms from opioid addiction.

Positive effects of mitragynine

  1. Pain relief: One of the most well-known effects of mitragynine is its ability to relieve pain. It acts on the pain receptors in the brain and can reduce both acute and chronic pain.

  2. Mood enhancement: Mitragynine can also have a mild euphoric effect, leading to an improvement in mood and well-being. Many people report an increase in energy and motivation after consuming kratom.

  3. Relaxation and stress relief: Another positive effect of mitragynine is its calming effect. It can help reduce anxiety, relieve stress and promote general relaxation.

Potential risks of mitragynine

Although mitragynine can have many positive effects, there are also potential risks associated with its consumption, especially when used excessively or abused:

  1. Addiction Potential: As with other substances that act on opioid receptors, mitragynine can be addictive, especially with long-term and excessive use.

  2. Side effects: Possible side effects of mitragynine include nausea, vomiting, dizziness, difficulty sleeping and constipation. In rare cases, more serious side effects such as liver damage have also been reported.

  3. Interactions with other drugs: People taking medications should be cautious because mitragynine has the potential to interact with other drugs and could cause unwanted side effects.


Mitragynine is undoubtedly a fascinating compound with a wide range of potential effects on the human body. It is important to understand these effects and treat the use of Kratom with caution and respect. Responsible use based on appropriate dosages and understanding one's own health can help reap the positive aspects of Mitragynine while minimizing potential risks. When in doubt, it is advisable to consult a doctor or substance abuse professional to make informed decisions about the use of Kratom.

0 views0 comments


Kratom Pulver

bottom of page